Page 120 - The Indian Optician Digital Edition November-December 2021

(22.32 ± 2.685) years with a range of 20 – 30 years. The mean axial inferior (SE G1:125.39 ± 14.48)
length was 24.28 ± 0.72 mm. (SE G2:117.17 ± 13.57) (p = 0.020),
nasal (SE G1: 69.55 ± 8.44) (SE
The table shows the values of the independent samples T-test G2: 65.83 ± 6.16) (p = 0.047)
in AXL Group 1 & 2, where a comparison of RNFL Thickness of the quadrants except temporal (SE
mean difference between AXL G1 and AXL G2 was done in each G1:61.89 ± 7.89) (SE G2:67.70 ±
quadrant. The table shows the mean value with its standard
deviation and statistically significant P-value for all quadrants. 9.94) (p = 0.009) quadrants and
also decrease in average RNFL
The table shows the values of Independent samples T-test in SE thickness (SE G1:94.92 ± 9.18)
Group 1 & 2, where a comparison of RNFL Thickness of the mean (SE G2:92.67 ± 9.02) (p = 0.315)
difference between SE G1 & SE G2 was done in each quadrant. with an increase in degree
The table shows the mean value with its standard deviation and of refractive error. [Table: 2]
statistically significant P-value for all quadrants. It is quite similar to a study
DISCUSSION by Sonika Porwal, Suneetha
Nithyanandam, Mary Joseph,
2
In this study, it was found that RNFL was thickest in the Andrew K Vasnaik.
superior (120.44 ± 17.45) and inferior (121.76 ± 14.57) quadrants Finding a thinner RNFL
and thinner in the temporal (64.46 ± 9.25) and nasal (67.91 ± 7.69) in more myopic eyes may
quadrants. Mohammad Salih , report a difference between the
3
nasal (64.9±9.8) and temporal (75.9±16.1) RNFL thickness, with the explain, to a certain degree,
nasal quadrant thinner than the temporal quadrant. However, the relationship between
it was also found that the temporal RNFL thickness was thinner glaucoma and myopia, which is
than the nasal quadrant. This was consistent with results reported known to be a risk factor for the
by other studies. 4,2 development of glaucoma.

The study demonstrated that the RNFL thickness decreases The clinical significance
in superior (AXLG1:121.40 ± 21.25) (AXL G2:119.42 ± 12.48) (p = 0.644), is that the thin polar RNFL
inferior (AXL G1:125.46 ± 15.67) (AXL G2:117.85 ± 12.37) (p =0.030), in myopes could be wrongly
nasal (AXL G1: 69.69 ± 8.47) (AXL G2: 66.03 ± 6.38) (p = 0.049) interpreted as glaucomatous
quadrants except temporal (AXL G1:63.91 ± 9.19) (AXL G2:65.03 ± change if one fails to take into
9.42) (p = 0.623) quadrants and also decrease in average RNFL account the effect of axial
thickness (AXL G1:95.60 ± 10.12) (AXL G2:92.15 ± 7.68) (p = 0.120) with length, by adjusting for it in the
an increase in the axial length. [Table: 1] This is quite similar to a current OCT nomograms. So, in
study by Sonika Porwal, Suneetha Nithyanandam, Mary Joseph, the eyes with myopia, especially
Andrew K Vasnaik. 2 those with moderate and high
myopia, a careful interpretation
So, after the comparison of the RNFL thickness of each of OCT is needed.
quadrant between two Axial length groups, it was observed
that the RNFL thickness in the inferior and nasal quadrants had The effect of myopia on
statistically decreased with increasing axial length, whereas the peripapillary RNFL thickness
superior, temporal, and average quadrants were statistically has been studied extensively,
insignificant with increasing AXL. although the results are
Similarly, it was found that in the comparison of RNFL conflicting. Several studies
thickness of each quadrant between two Spherical Equivalent found that when myopia and
groups, the RNFL thickness in the inferior, nasal and temporal axial length increased, average
quadrants statistically decreased with increasing SE, whereas the RNFL thickness decreased.
superior and average quadrants were statistically insignificant They also discovered that high
with an increasing degree of refractive error. myopes had thinner RNFLs
than low myopes, as well as
The study demonstrated that RNFL thickness decrease in differing topographic profiles,
superior ( SE G1:120.66 ± 15.96) (SE G2:120.17 ± 19.46) (p = 0.909), leading to the conclusion that

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