Page 38 - The Indian Optician Digital Edition Jan-Feb 2020

ACUTE RETINOPATHY Only three patients showed fully both, were detected in 67%.
CAN LEAD TO VISION reversible changes. Another three The research team hopes these
had prolonged and likely permanent
LOSS IN PXE PATIENTS vision loss due primarily to central findings will contribute to the
understanding of variable ocular
A research team based in sub-retinal hyper reflective material disease progress in PXE and provide
Germany has found that acute originating from angioid streaks.
insights into the autoimmune
retinopathy may, in some cases, Anti-retinal or anti-RPE antibodies, or phenomena of the posterior pole.
explain vision loss and other disease
manifestations in patients with OPTICAL IMAGER TO IMPROVE DRY EYE
pseudoxanthoma elasticum (PXE). DIAGNOSIS AND TREATMENT

The team appraised 167 patients new non-invasive optical Advanced Optical Methods Ltd.
with PXE from May 2013 to October A imaging system that promises in Israel. “Our Tear Film Imager is
2018. The subjects were asked to go to improve diagnosis and treatments the first device that can be used in
through various imaging exams such for dry eye disease has been the ophthalmology or optometry
as fundus photography, fundus auto- developed by Israel researchers. setting to image the tear film and
fluorescence (FAF), OCT, fluorescein Dry eye usually occurs when there distinguish its inner layers with
angiography (FA), indocyanine green is instability in the inner layer of the nanometer resolution.”
angiography (ICGA) and, in some tear film that protects the outside of
cases, electro-retinography and the eye. The new instrument uses an
anti-retinal pigment epithelium (RPE) eye-safe halogen light to illuminate
antibody testing. The researchers, including the eye, and then analyses the
those from the Optical Society in full spectrum of light reflection
The study reported in JAMA the US, said that most cases of dry happening over time and space.
Ophthalmology states that the eye are diagnosed using patient The measurements, completed
researchers identified nine patients questionnaires, which may be automatically in just 40 seconds,
with acute retinopathy, with subjective and are not ideally used are used to reconstruct the
symptoms ranging from short-term, to identify the cause of the disease. structures found in the front of the
reversible alterations to irreversible Objective methods for examining eye, allowing ophthalmologists to
vision loss. Also, all nine had fundus the tear film tend to be invasive accurately measure the tear film
alterations, including similarities and cannot track rapid changing inner layers, particularly the aqueous
with multiple evanescent white dynamics, which are altered with sublayer which plays an important
dot syndrome. every blink. role in dry eye.

The various tests indicate that, The study, published in the The Imager measured the
of the nine with retinopathy, 67% Optical Society (OSA) journal Applied tear film consistently including
experienced visual acuity reductions. Optics, describe the device’s ability blinks every few seconds, and the
All patients revealed characteristic to perform spectral measurements measurements correlated well with
fundus features with temporary across a large field of view in a matter other partially invasive, commonly
appearance of partly confluent outer of seconds. The researchers report used dry eye diagnostic techniques,
retinal whitish dots at the posterior that the imager can acquire fast the study noted.
pole, which corresponded with areas and consistent measurements from The research study was
of hyper-autofluorescence on fundus human eyes even when blinking. performed at AdOM Advanced
FAF, loss of the ellipsoid band on OCT “Up to 60 percent of Optical Methods laboratory.
and associated scotomata. The FA ophthalmology office visits are The proof of concept, unique
and late-phase ICGA imaging showed due to dry eye, pointing to the method and design that enable
associated hyperfluorescence need for a non-invasive and highly measurement of ultra-thin tear layers
and hypocyanescence. accurate device for diagnosis in the with nanometer resolution were
Electroretinography revealed a office setting,” said research team developed by AdOM’s development
variable reduction of amplitudes. leader Dr. Yoel Arieli from AdOM team led by Dr. Yoel Cohen.

| JAN-FEB 2020 | 34 OPHTHALMIC NEWS

January-February 2020 SK News IDML.indd 6 02/15/2020 20:33