Page 36 - The Indian Optician Digital Edition November-December 2021
P. 36

BDNF TO                           degeneration of RGCs seen in glaucoma, validating the ability of

          PREVENT SIGHT                     this treatment to protect these cells.
          LOSS DUE TO                       MIKAJAKI INTRODUCES EYELIB
          GLAUCOMA                          DIAGNOSTIC STATION



             An on-going study aims to         Swiss startup and ophthalmology expert
          find out if a naturally occurring   Mikijaki has partnered with engineering
          protein in the body can be        group Segula Technologies to develop
          used to prevent sight loss from   the first operational series of EyeLib, an
          glaucoma. The study funded by     innovative automated diagnostic station
          Fight for Sight in partnership    that has the potential to transform the way
          with the Spectacle Makers’        the growing number of patients with vision
          Charity and Glaucoma UK, is       disorders are managed.
          being conducted at the Cardiff       EyeLib combines artificial intelligence (AI)
          University, UK.                   with robotics to enable fast, fully automated
             Researchers are exploring if   advanced and complete ophthalmological
          a neuroprotective agent called    diagnoses and resulting referrals to the
          brain-derived neurotrophic        correct specialists. The device is presented
          factor (BDNF) can be released     as a mobile station that is automatically
          in a controlled way from the      adjustable to different morphologies.
          blood when stimulated with           The patient has to answer an online
          an ultrasound as a targeted       questionnaire through a virtual agent
          treatment for glaucoma.           (chatbot) driven by AI, and benefits from
             The Cardiff University         a rapid succession of opto-electronic
          research is being led by          measurements of the eye. It takes just a
          Dr Andrew Want. “Glaucoma         few minutes for EyeLib™ to analyse around
          is linked to high eye pressure    100 objective parameters and generate a
          and so current treatments for     report that also includes highly detailed
          the condition are aimed at the    imaging of the eye’s anatomical and optical structures. These
          reduction of this pressure. We    results are then combined with the subjective data collected by
          want to take the benefits of      the questionnaire, to generate an all-inclusive pre-diagnosis by
          BDNF seen in prior work closer    means of several artificial intelligence algorithms.
          to a viable clinical treatment       The first prototypes of the EyeLib cabins are already in
          by addressing several of the      place in Nantes and Paris, France, and with the help of Segula
          difficulties in delivery and dose   Technologies, Mikajaki has also registered some twenty pre-
          control,” said Dr Andrew.         orders in several European countries. The EyeLib is easy to
             The scientists will be         industrialise, fast and accessible to people of all sizes, as well as
          using a genetic model in the      to wheelchair users.
          lab to control the optimum           Dr Michael Assouline, co-founder and medical director at
          exposure times and frequency      Mikajaki reveals: “In less than two and a half years, we have
          of ultrasound needed for          been able to complete the prototype development phase and
          BDNF. Eye pressure levels         create an innovative process to generate an intelligent report
          of a glaucoma model will          of great medical value. We see this as a revolutionary solution
          be monitored over a month         to the problem of the shortage of ophthalmologists in France
          and intermittent ultrasound       and worldwide. We hope that this cooperation will enable
          treatments will be given to       us to make our vision a concrete reality, widely distributed
          determine if BDNF reduces the     throughout the world.”


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