Page 20 - The Indian Optician Digital Edition July-August 2021
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GENETIC STUDY                     HONEY EYE DROPS FOR DRY EYE

          DISCOVERS
          50 NEW EYE                           Manuka honey eye drops have been found to be effective in the
          COLOUR GENES                       treatment of meibomian gland dysfunction which leads to dry eye.

                                               A new research study, titled the Standard Patient Evaluation of
                                             Eye Dryness (SPEED) was done by assigning 59 dry eye patients
             The genetics of human eye       with either regular lubricating eye drops or Optimel 16% manuka
          colour is much more complex        honey eye-drops.  The SPEED was measured in each patient at the
          than hitherto envisaged,           start of the trial and at a follow up appointment three weeks later.
          according to a new study             According to the report published in the British Journal of
          published in Science Advances.
                                             Ophthalmology, different ocular surface parameters were graded
             An international team of        during a slit lamp examination. Three weeks later, the researchers
          researchers led by King’s College  noted that those treated with conventional drops showed
          London and Erasmus University      minimal difference in SPEED score, while patients who received
          Medical Center Rotterdam           Optimel drops had a noticeable difference in SPEED score. The
          have identified 50 new genes       Optimel group also showed improvements in lid margin redness,
          for eye colour in what is          conjunctival redness, corneal surface stain, and meibum quality
          considered to be the largest       and expressibility.
          study of its kind till date. The     The researchers thus concluded that the manuka honey eye
          study encompassed the genetic      drops offered a good option for treating patients with meibomian
          analysis of nearly 195,000 people   gland dysfunction.
          across Europe and Asia.
             Co-senior author Dr Pirro
          Hysi, King’s College London,
          shared that the findings are
          exciting because they represent     POOR EYE HEALTH LINKED TO
          progress in understanding
          the genes that cause one of         HIGHER MORTALITY RISK
          “the most striking features”
          on human faces. He said: “The          A new international report by the Lancet Global Health
          findings will improve our           Commission on Global Eye Health reveals that around 1.1 billion
          understanding of many diseases      people experience sight loss due to lack of access to eye care
          such as pigmentary glaucoma         services. The report further states that 90% of sight loss could be
          and ocular albinism, that we        avoided and that people with poor eye health have a 2.6 times
          know are associated with            higher risk of mortality than those without sight loss.
          specific pigmentation levels.”
                                                 International Agency for the Prevention of Blindness chief
             Dr Manfred Kayser, Erasmus       executive, Peter Holland, described the research as a “landmark
          University Medical Center           report.” He says, “It cannot be right that so many people in
          Rotterdam, co-senior author         our world go without access to eye care when the majority of
          said: “This study delivers the      treatments are affordable and have been around for many years.”
          genetic knowledge needed to
          improve eye colour prediction          “The Lancet Global Commission on Global Eye Health proves
          from DNA as already applied         once and for all that good quality eye care has a vital effect
          in anthropological and forensic     on people’s everyday lives, enabling children to benefit from
          studies, but with limited           education, ensuring working adults keep their jobs and that
          accuracy for the non-brown and      older people can participate in their families and communities,”
          non-blue eye colours.”              Mr Holland added.


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